{"id":216,"date":"2010-05-09T18:57:22","date_gmt":"2010-05-09T16:57:22","guid":{"rendered":"http:\/\/www.pjh.fr\/wordpress\/?page_id=216"},"modified":"2010-05-09T18:58:41","modified_gmt":"2010-05-09T16:58:41","slug":"abvd","status":"publish","type":"page","link":"http:\/\/www.pjh.fr\/wordpress\/?page_id=216","title":{"rendered":"ABVD"},"content":{"rendered":"<p><strong>Indications principales :<\/strong><\/p>\n<ul>\n<li> Lymphomes de Hodgkin (1\u00e8re ligne)<\/li>\n<\/ul>\n<table style=\"background-color: #d3d3d3; width: 100%;\" border=\"0\" cellspacing=\"0\" cellpadding=\"2\">\n<tbody>\n<tr>\n<td style=\"width: 33%; background-color: #d3d3d3;\"><strong><span style=\"color: #ff0000;\">DOXORUBICINE <\/span><\/strong><\/td>\n<td style=\"width: 33%;\">ADRIBLASTINE<\/td>\n<td>25 mg\/m<sup>2<\/sup>\/j \u00e0 J1 et J15<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td colspan=\"2\">Perfusion de 10 mn dans 100 ml de G5%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%;\" border=\"1\" cellspacing=\"0\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J1<\/strong><\/td>\n<td align=\"center\">J2<\/td>\n<td align=\"center\">J3<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J8<\/strong><\/td>\n<td align=\"center\">J9<\/td>\n<td align=\"center\">J10<\/td>\n<td align=\"center\">J11<\/td>\n<td align=\"center\">J12<\/td>\n<td align=\"center\">J13<\/td>\n<td align=\"center\">J14<\/td>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J15<\/strong><\/td>\n<td align=\"center\">J16<\/td>\n<td align=\"center\">J17<\/td>\n<td align=\"center\">J18<\/td>\n<td align=\"center\">J19<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J22<\/strong><\/td>\n<td align=\"center\">J23<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\">J27<\/td>\n<td align=\"center\"><strong>J28<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td style=\"background-color: #ff6347; text-align: center;\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"background-color: #d3d3d3; width: 100%;\" border=\"0\" cellspacing=\"0\" cellpadding=\"2\">\n<tbody>\n<tr>\n<td style=\"width: 33%; background-color: #d3d3d3;\"><strong><span style=\"color: #ff0000;\">BLEOMYCINE <\/span><\/strong><\/td>\n<td style=\"width: 33%;\">BLEOMYCINE<\/td>\n<td>10 mg\/m<sup>2<\/sup>\/j \u00e0 J1 et J15<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td colspan=\"2\">IV. Intratubulaire 5mn seringue 10ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%;\" border=\"1\" cellspacing=\"0\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J1<\/strong><\/td>\n<td align=\"center\">J2<\/td>\n<td align=\"center\">J3<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J8<\/strong><\/td>\n<td align=\"center\">J9<\/td>\n<td align=\"center\">J10<\/td>\n<td align=\"center\">J11<\/td>\n<td align=\"center\">J12<\/td>\n<td align=\"center\">J13<\/td>\n<td align=\"center\">J14<\/td>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J15<\/strong><\/td>\n<td align=\"center\">J16<\/td>\n<td align=\"center\">J17<\/td>\n<td align=\"center\">J18<\/td>\n<td align=\"center\">J19<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J22<\/strong><\/td>\n<td align=\"center\">J23<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\">J27<\/td>\n<td align=\"center\"><strong>J28<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td style=\"background-color: #ff6347; text-align: center;\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"background-color: #d3d3d3; width: 100%;\" border=\"0\" cellspacing=\"0\" cellpadding=\"2\">\n<tbody>\n<tr>\n<td style=\"width: 33%; background-color: #d3d3d3;\"><strong><span style=\"color: #ff0000;\">VINBLASTINE <\/span><\/strong><\/td>\n<td style=\"width: 33%;\">VELBE<\/td>\n<td>6 mg\/m<sup>2<\/sup>\/j \u00e0 J1 et J15<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td colspan=\"2\">IV. Intratubulaire 5mn seringue 10ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%;\" border=\"1\" cellspacing=\"0\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J1<\/strong><\/td>\n<td align=\"center\">J2<\/td>\n<td align=\"center\">J3<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J8<\/strong><\/td>\n<td align=\"center\">J9<\/td>\n<td align=\"center\">J10<\/td>\n<td align=\"center\">J11<\/td>\n<td align=\"center\">J12<\/td>\n<td align=\"center\">J13<\/td>\n<td align=\"center\">J14<\/td>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J15<\/strong><\/td>\n<td align=\"center\">J16<\/td>\n<td align=\"center\">J17<\/td>\n<td align=\"center\">J18<\/td>\n<td align=\"center\">J19<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J22<\/strong><\/td>\n<td align=\"center\">J23<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\">J27<\/td>\n<td align=\"center\"><strong>J28<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td style=\"background-color: #ff6347; text-align: center;\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"background-color: #d3d3d3; width: 100%;\" border=\"0\" cellspacing=\"0\" cellpadding=\"2\">\n<tbody>\n<tr>\n<td style=\"width: 33%; background-color: #d3d3d3;\"><strong><span style=\"color: #ff0000;\">DACARBAZINE <\/span><\/strong><\/td>\n<td style=\"width: 33%;\">DETICENE<\/td>\n<td>375 mg\/m<sup>2<\/sup>\/j \u00e0 J1 et J15<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td colspan=\"2\">IV. Intratubulaire 5mn seringue 10ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%;\" border=\"1\" cellspacing=\"0\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J1<\/strong><\/td>\n<td align=\"center\">J2<\/td>\n<td align=\"center\">J3<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J8<\/strong><\/td>\n<td align=\"center\">J9<\/td>\n<td align=\"center\">J10<\/td>\n<td align=\"center\">J11<\/td>\n<td align=\"center\">J12<\/td>\n<td align=\"center\">J13<\/td>\n<td align=\"center\">J14<\/td>\n<td style=\"background-color: #ff6347;\" align=\"center\"><strong>J15<\/strong><\/td>\n<td align=\"center\">J16<\/td>\n<td align=\"center\">J17<\/td>\n<td align=\"center\">J18<\/td>\n<td align=\"center\">J19<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\"><strong>J22<\/strong><\/td>\n<td align=\"center\">J23<\/td>\n<td align=\"center\">&#8230;<\/td>\n<td align=\"center\">J27<\/td>\n<td align=\"center\"><strong>J28<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"background-color: #ff6347;\" align=\"center\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td style=\"background-color: #ff6347; text-align: center;\">x<\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<td align=\"center\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 100%;\" border=\"0\" cellspacing=\"0\" cellpadding=\"2\">\n<tbody>\n<tr style=\"background-color: #d3d3d3;\" valign=\"top\">\n<td style=\"width: 180px;\"><strong>Rythme :<\/strong><\/td>\n<td><strong> J1=J29<\/strong><\/td>\n<\/tr>\n<tr valign=\"top\">\n<td><strong>Dur\u00e9e :<\/strong><\/td>\n<td>3 \u00e0 8 cycles selon l&rsquo;\u00e9tendue de la maladie<\/td>\n<\/tr>\n<tr style=\"background-color: #d3d3d3;\" valign=\"top\">\n<td valign=\"top\"><strong>Traitements associ\u00e9s :<\/strong><\/td>\n<td>\n<ul>\n<li><strong>+\/- SOLUMEDROL <\/strong>120 mg\/m<sup>2<\/sup> \u00e0 J1 et J15 (ABVD-Mp)<\/li>\n<li>Anti-naus\u00e9eux : <strong>anti-H3 <\/strong><\/li>\n<li>Facteurs de croissance h\u00e9matopo\u00ef\u00e9tiques: non syst\u00e9matiques<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr valign=\"top\">\n<td><strong>Risque \u00e9m\u00e9tisant : <\/strong><\/td>\n<td>\u00e9lev\u00e9<\/td>\n<\/tr>\n<tr style=\"background-color: #d3d3d3;\">\n<td><strong>Alop\u00e9cie :<\/strong><\/td>\n<td>non constante (28% apr\u00e8s 4 ABVD, 15% apr\u00e8s 2 ABVD)<\/td>\n<\/tr>\n<tr valign=\"top\">\n<td><strong>Pr\u00e9cautions :<\/strong><\/td>\n<td>D\u00e9tic\u00e8ne : perfusion \u00e0 l&rsquo;abri de la lumi\u00e8re<\/td>\n<\/tr>\n<tr style=\"background-color: #d3d3d3;\" valign=\"top\">\n<td valign=\"top\"><strong>Doses cumul\u00e9es max :<br \/>\n<\/strong><\/td>\n<td><strong>Bl\u00e9omycine :<\/strong> ne pas d\u00e9passer la dose totale cumul\u00e9e de deux cents milligrammes (200 mg)<br \/>\n<strong>Doxorubicine :<\/strong> dose maximal de cinq cent cinquante milligrammes par m\u00e8tre carr\u00e9 (550 mg\/m2)<\/td>\n<\/tr>\n<tr valign=\"top\">\n<td valign=\"top\"><strong>Surveillance :<\/strong><\/td>\n<td>TA, FC 3x\/J<br \/>\nNFS avant J1 et J15<\/td>\n<\/tr>\n<tr style=\"background-color: #d3d3d3;\" valign=\"top\">\n<td><strong>Co\u00fbt par cycle :<\/strong><\/td>\n<td>162 Euros<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n<div class=\"pdf24Plugin-cp\"> \t<form name=\"pdf24Form0\" method=\"post\" action=\"https:\/\/doc2pdf.pdf24.org\/wordpress.php\" target=\"pdf24PopWin\" onsubmit=\"var pdf24Win = window.open('about:blank', 'pdf24PopWin', 'resizable=yes,scrollbars=yes,width=600,height=250,left='+(screen.width\/2-300)+',top='+(screen.height\/3-125)+''); 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J8 J9 J10 J11 J12 J13 J14 J15 J16 J17 J18 J19 &#8230; J22 J23 &#8230; J27 J28 x x BLEOMYCINE BLEOMYCINE 10 mg\/m2\/j \u00e0 J1 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":210,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/216"}],"collection":[{"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=216"}],"version-history":[{"count":19,"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/216\/revisions"}],"predecessor-version":[{"id":244,"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/216\/revisions\/244"}],"up":[{"embeddable":true,"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/210"}],"wp:attachment":[{"href":"http:\/\/www.pjh.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}